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36,37 Zonula occludens (ZO), including ZO-1 and its homologs ZO-2 and ZO-3, is a group of PDZ-related scaffolding proteins that belong to the superfamily of membrane-associated guanylate kinase-like proteins, possessing sites of three tandem PDZ domains at the N-terminus 38,39 (Figure 1)

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This research blend combines a NAD + -associated coenzyme component , a mitochondria-derived peptide , and an NNMT-pathway small-molecule analog into a single laboratory formulation for investigational use