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doi: 10.1016/j.hlc.2009.05.685 Astaxanthin vs placebo on arterial stiffness, oxidative stress and inflamation in renal transplant patients (Xanthin): A randomised controlled trial

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Many of these trials recruited terminal or end-stage patients, for whom any sort of treatment is unlikely to have an effect, and they often recruited cohorts with mixed cancers, which may respond differentially to IVC depending on the underlying mechanisms involved