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Ascorbic acid (vitamin C) is a reducing agent that binds to ARE, inhibits Nrf2 translocation to DNA, and decreases the levels of g-GCSl mRNA and GSH

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The historical discovery of SRXN1 Throughout the late twentieth century, research into oxidative stress mechanisms had largely focused on identifying key enzymatic players such as catalase, superoxide dismutase and glutathione peroxidase