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Metformin contraindications You should not use metformin if you: Are allergic to metformin Have severe kidney disease Have metabolic acidosis or diabetic ketoacidosis Are younger than 10 years old Are breastfeeding or are planning to breastfeed Talk to a healthcare professional before using metformin if you: Have kidney disease Have high ketone levels in your blood or urine Have heart disease, or congestive heart failure Have liver disease Use insulin or other oral diabetes medications Have a severe infection Have chronic alcoholism Are 65 or older Are pregnant or are planning to become pregnant Who can take metformin

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Its structural stability and controlled degradation profile make it suitable for complex experimental designs