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In rats, daily application of 1% w / w BCP emulgel improved closure and remodeling, with up-regulation of laminin-γ2, desmoglein-3, and collagen, reduced pro-inflammatory cytokines (TNF-α, IFN-γ, IL-1β, IL-6), increased IL-10, and antioxidant activity (elevated glutathione peroxidase, GPx), without hepatic or renal toxicity compared with comparators [32]

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10.1016/j.jep.2007.01.006 54 JiaoH

One of the key ingredients in this formula is S